The Mouse Anti-c-CBL Antibody from MyBioSource.com is a Mouse Monoclonal antibody to Cbl. This antibody recognizes Human, Mouse, and Rat antigen. The Mouse Anti-c-CBL Antibody has been validated for the following applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
CBL Antibody, C-CBL Antibody, Oncogene CBL2 Antibody, RING finger protein 55 Antibody, Proto-oncogene c-Cbl Antibody, RNF55 Antibody, CBL2 Antibody, FRA11B Antibody, NSLL Antibody Description: Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling